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The Code Breaker

by Walter Isaacson · Walter Isaacson

Biography of Jennifer Doudna that doubles as a narrative history of CRISPR, covering the race between competing labs, the patent fight with the Broad Institute, and the ethical arguments over editing human embryos.

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More resources on CRISPR Technology

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addgene.org

Addgene is a nonprofit plasmid repository and resource for genetic engineering. It provides access to thousands of plasmids and CRISPR tools, plus detailed protocols, educational materials, and community resources for researchers.

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CRISPR Journal

Peer-reviewed journal from Mary Ann Liebert publishing primary research, reviews, and commentary on genome editing, spanning delivery methods, base and prime editing, agriculture, therapeutics, and the policy debates around clinical use.

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Addgene CRISPR Guide

Reference pages from the nonprofit plasmid repository explaining Cas9 biology, guide design, delivery, and screening, with links to validated plasmids and bench protocols. Gives newcomers enough grounding to plan a first editing experiment.

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Genome Editing with CRISPR-Cas9

Short animation from MIT's McGovern Institute, made with Feng Zhang's lab, showing how Cas9 is guided to a DNA target, cuts both strands, and how the repair pathways enable gene knockout or insertion.

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A Crack in Creation

First-hand account from the Berkeley lab that developed CRISPR-Cas9 as an editing tool, tracing the bacterial immunity research behind it and then confronting germline editing, patents, and the ethics of a technology moving faster than its oversight.

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CRISPR People

Bioethicist and law professor Henry T. Greely reconstructs He Jiankui's 2018 gene-edited babies case, then examines the science, regulation, and ethical arguments around heritable human genome editing and when, if ever, it should be permitted.

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