---
title: Neurophysiology
description: This study focuses on the functioning of the nervous system, specifically how neurons generate and transmit electrical signals. Learners will understand action potentials, ion channels, and how neural circuits process sensory information and control motor output.
category: sciences
subcategory: neuroscience
difficulty: beginner, intermediate, advanced
url: /subject/neurophysiology
---

# Neurophysiology

This study focuses on the functioning of the nervous system, specifically how neurons generate and transmit electrical signals. Learners will understand action potentials, ion channels, and how neural circuits process sensory information and control motor output.

## Available Resources

1 Books • 4 Courses • 4 Websites

## Websites

### 1. NeuroElectro

Literature-mined database of electrophysiological measurements, such as resting membrane potential, input resistance and spike properties, compiled from published papers for many neuron types. Use it to compare how neuron classes differ and to find source studies for model parameters.

**Difficulty:** Beginner | **Price:** Free

**Link:** https://neuroelectro.org/

**Tags:** electrophysiology, neuron-types, membrane-properties, neuroinformatics, literature-mining

### 2. NeuronIF

Yale-developed simulation environment by Michael Hines and Ted Carnevale for building biophysically detailed models of single neurons and networks, scripted in Python or hoc. Includes documentation and tutorials for simulating membrane potentials, ion channel kinetics, and synaptic input.

**Difficulty:** Beginner | **Price:** Free

**Link:** https://www.neuron.yale.edu/neuron/

**Tags:** neuron-simulator, computational-neuroscience, compartmental-modeling, ion-channels, neural-simulation

### 3. Allen Brain Atlas

The Allen Institute's portal to open brain-mapping datasets: gene expression atlases, cell type databases, connectivity maps, and viewers for human, mouse, and non-human primate brains. Useful once you need primary data rather than textbook summaries.

**Difficulty:** Beginner | **Price:** Free

**Link:** https://portal.brain-map.org/

**Tags:** brain atlas, gene expression, connectomics, open data, allen institute

### 4. hhmi.org/biointeractive

HHMI BioInteractive offers free, interactive biology resources—animations, videos, virtual labs, and lesson plans—that explain neurophysiology concepts and neuroscience experiments for students and educators.

**Difficulty:** Intermediate | **Language:** English | **Price:** Free

**Link:** https://hhmi.org/biointeractive

**Tags:** websites, science-research, neuroscience

## Courses

### 1. Introduction to Neural Computation (MIT 9.40)

**Author:** Michale Fee, Daniel Zysman

Quantitative models of brain function: mathematical descriptions of neurons, responses to sensory stimuli, simple networks, statistical inference and decision making, plus analysis tools such as convolution, spectral analysis and principal components. Includes 20 lecture videos, slides and problem sets.

**Difficulty:** Intermediate | **Price:** Free

**Link:** https://ocw.mit.edu/courses/9-40-introduction-to-neural-computation-spring-2018/

**Tags:** computational-neuroscience, neural-coding, hodgkin-huxley, spectral-analysis, principal-component-analysis

### 2. Fundamentals of Neuroscience, Part 1: The Electrical Properties of the Neuron

**Author:** David Cox

HarvardX's first of three courses on neuroscience, covering the electrical behavior of single neurons: resting potential, action potentials, and synaptic transmission. Includes an interactive neuron simulator so learners can model how membrane currents produce firing.

**Difficulty:** Intermediate | **Price:** Free

**Link:** https://www.edx.org/learn/neuroscience/harvard-university-fundamentals-of-neuroscience-part-1-the-electrical-properties-of-the-neuron

**Tags:** neurophysiology, action-potential, membrane-biophysics, neurons, resting-potential

### 3. Neurophysiology

Peking University course taught by Yan Zhang and Yulong Li covering neuroanatomy, neuronal cell biology, resting potentials and the Nernst equation, ion channels, neurotransmitter release, and synaptic plasticity. Learners finish able to explain how neurons generate and transmit signals.

**Difficulty:** Intermediate | **Language:** English | **Price:** Free

**Link:** https://www.coursera.org/learn/advanced-neurobiology1

**Tags:** courses, science-research, neuroscience

### 4. Computational Neuroscience

**Author:** Adrienne Fairhall, Rajesh Rao

University of Washington course on how neurons and networks represent and process information, covering neural encoding and decoding, information theory, single-neuron biophysical models, synaptic plasticity and network learning. Learners can build and interpret quantitative models of neural computation through programming exercises.

**Difficulty:** Intermediate | **Language:** English | **Price:** Free

**Link:** https://www.coursera.org/learn/computational-neuroscience

**Tags:** computational-neuroscience, neural-coding, information-theory, neuron-models, synaptic-plasticity

## Books

### 1. From Neuron to Brain

**Author:** John G. Nicholls, A. Robert Martin, Bruce G. Wallace

Third edition (1992) of the classic cellular neuroscience textbook, explaining nervous system function from ion channels and membrane biophysics through synaptic transmission, development, sensory systems and motor control. Grounded in key experiments, it teaches how neurons signal and communicate.

**Difficulty:** Intermediate | **Language:** English | **Price:** Paid

**Link:** https://www.amazon.com/dp/0878935800?tag=edmonddante07-20

**Tags:** books, science-research, neuroscience

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